Sense and specificity: a molecular identity far nociceptors

被引:133
作者
Caterina, MJ [1 ]
Julius, D [1 ]
机构
[1] Univ Calif San Francisco, Dept Cellular & Mol Pharmacol, San Francisco, CA 94143 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0959-4388(99)00009-4
中图分类号
Q189 [神经科学];
学科分类号
071006 [神经生物学];
摘要
Recent cloning efforts have identified families of ligand- or voltage-gated ion channels that are expressed by pain-sensing primary afferent neurons. Pharmacological, electrophysiological and genetic studies are beginning to reveal how these signaling molecules specify roles for subsets of sensory neurons in the pain pathway.
引用
收藏
页码:525 / 530
页数:6
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