Poxviruses aren't stuPYD

被引：9

作者：

Benedict, CA ^{[1
]}

Ware, CF ^{[1
]}

机构：

[1] La Jolla Inst Allergy & Immunol, Div Mol Immunol, San Diego, CA 92121 USA

来源：

IMMUNITY | 2005年 / 23卷 / 06期

关键词：

D O I：

10.1016/j.immuni.2005.11.008

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Pathogens utilize many strategies to dampen the host inflammatory response. In this issue of Immunity, a report by Johnston and colleagues reveals a poxvirus strategy that inhibits the inflammasome, arresting secretion of interleukin-1-related cytokines, thus silencing key alarms that mobilize host defenses.

引用

页码：553 / 555

页数：3

共 9 条

[1] NALP3 forms an IL-lβ-Processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
Agostini, L
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Barrett, JW
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[8] The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-κB and pro-caspase-1 regulation
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