F-18FDG positron emission tomography demonstrates resolution of non-Hodgkin's lymphoma of the parotid gland in a patient with Sjogren's syndrome - Before and after anti-CD20 antibody rituximab therapy

被引:34
作者
Shih, WJ [1 ]
Ghesani, N
Zhuang, HM
Alavi, A
Schusper, S
Mozley, D
机构
[1] Vet Adm Med Ctr, Nucl Med Serv, Lexington, KY 40511 USA
[2] Univ Penn, Med Ctr, Philadelphia, PA 19104 USA
[3] Univ Kentucky, Med Ctr, Lexington, KY USA
关键词
fluorine-18; fluorodeoxyglucose; monoclonal antibody therapy; non-Hodgkin's lymphoma; rituximab; Sjogren's syndrome;
D O I
10.1097/00003072-200202000-00019
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 [临床医学]; 100207 [影像医学与核医学]; 1009 [特种医学];
摘要
Salivary gland non-Hogdgkin's lymphoma (NHL) in patients with Sjogren's syndrome frequently develops from rheumatoid factor B cells. The authors describe a patient with NHL of the parotid glands associated with Sjogren's syndrome whose initial positron emission tomographic (PET) findings included abnormal F-18 fluorodeoxyglucose (FDG) uptake in the parotid glands. After rituximab therapy, a follow-up PET study confirmed a positive response to treatment. This illustrates that F-18 FDG PET can be used to monitor the therapeutic response of NHL parotid glands associated with Sjogren's syndrome.
引用
收藏
页码:142 / 143
页数:2
相关论文
共 7 条
[1]
Rituximab (anti-CD20 monoclonal antibody) as single first-line therapy for patients with follicular lymphoma with a low tumor burden:: clinical and molecular evaluation [J].
Colombat, P ;
Salles, G ;
Brousse, N ;
Eftekhari, P ;
Soubeyran, P ;
Delwail, V ;
Deconinck, E ;
Haïoun, C ;
Foussard, C ;
Sebban, C ;
Stamatoullas, A ;
Milpied, N ;
Boué, F ;
Taillan, B ;
Lederlin, P ;
Najman, A ;
Thièblemont, C ;
Montestruc, F ;
Mathieu-Boué, A ;
Benzohra, A ;
Solal-Céligny, P .
BLOOD, 2001, 97 (01) :101-106
[2]
Hainsworth JD, 2000, BLOOD, V95, P3052
[3]
INCREASED RISK OF LYMPHOMA IN SICCA SYNDROME [J].
KASSAN, SS ;
THOMAS, TL ;
MOUTSOPOULOS, HM ;
HOOVER, R ;
KIMBERLY, RP ;
BUDMAN, DR ;
COSTA, J ;
DECKER, JL ;
CHUSED, TM .
ANNALS OF INTERNAL MEDICINE, 1978, 89 (06) :888-892
[4]
Martin T, 2000, ARTHRITIS RHEUM-US, V43, P908, DOI 10.1002/1529-0131(200004)43:4<908::AID-ANR24>3.0.CO
[5]
2-K
[6]
Romer Wolfgang, 1998, Clin Positron Imaging, V1, P101, DOI 10.1016/S1095-0397(98)00004-1
[7]
Lymphomas in patients with Sjogren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses [J].
Royer, B ;
CazalsHatem, D ;
Sibilia, J ;
Agbalika, F ;
Cayuela, JM ;
Soussi, T ;
Maloisel, F ;
Clauvel, JP ;
Brouet, JC ;
Mariette, X .
BLOOD, 1997, 90 (02) :766-775