Prevention of atrial tachyarrhythmias after non-cardiac thoracic surgery by infusion of magnesium sulfate

被引:46
作者
Terzi, A
Furlan, G
Chiavacci, P
DalCorso, B
Luzzani, A
DallaVolta, S
机构
[1] OSPED CIVILE,SERV ANESTHESIOL 2,AZIENDA OSPEDALIERA VERONA,I-37126 VERONA,ITALY
[2] UNIV VERONA,I-37100 VERONA,ITALY
[3] UNIV PADUA,SCH MED,DIV CARDIOL,DEPT CLIN MED,PADUA,ITALY
关键词
postoperative atrial tachyarrhythmia; thoracic surgery; magnesium sulfate;
D O I
10.1055/s-2007-1012041
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The possible role of magnesium sulfate (MgSO4) infusion in the prevention of atrial tachyarrhythmias after non-cardiac thoracic surgery was evaluated through a prospective study of two hundred patients who underwent non-cardiac thoracic surgery. The patients (who fulfilled the following requirements among others: no myocardial infarction in the previous six months, normal renal function, no use of digitalis or antiarrhythmic drugs, not undergone emergency operations or video-assisted thoracic surgery), were randomly assigned to receive MgSO4 infusion in all circumstances (Mg group), or either no treatment or, if aged over 70 or in cases of pneumonectomy or an intrapericardial procedure, application of digoxin starting on the day of operation (control group). 95 patients were enrolled in the Mg group and 105 in the control group. 93 patients in the Mg group and 101 in the control group were evaluated. Post-operative atrial tachyarrhythmias, mainly atrial fibrillation, occurred in 10 patients (10.7%) in the Mg group and in 27 (26.7%) patients in the control group (chi(2)=7.009, df=1, p=0.008). It is concluded that infusion of MgSO4 is an effective means of reducing the incidence of atrial tachyarrhythmias after non-cardiac thoracic surgery.
引用
收藏
页码:300 / 303
页数:4
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