Successful treatment of earlobe keloids in the pediatric population

被引:25
作者
Hamrick, Miller [1 ]
Boswell, William [1 ]
Carney, David [1 ]
机构
[1] Mem Hlth Univ Med Ctr, Dept Pediat Surg, Savannah, GA 31406 USA
关键词
Keloid; Kenalog; Interferon alfa-2b; Fibroblast; Alpha(1)-antitrypsin; Proteoglycans; Hyaluronic acid; Alpha-2-macroglobulin; TGF-beta; bFGF; PATHOGENESIS; MANAGEMENT;
D O I
10.1016/j.jpedsurg.2008.10.058
中图分类号
R72 [儿科学];
学科分类号
100202 [儿科学];
摘要
Background: Keloid scars present a difficult treatment challenge. Recently, intralesional steroid injection has become a common treatment modality [Akoz et al. Aesthetic Plast Sing. 2002:6:184-188; Studdiford et al. JABFM. 2008;21:149-152]. Although this has become a proven treatment technique, there is no standard injection protocol to which treating physicians commonly adhere. We hypothesize that timing of steroid injection may improve outcomes using this treatment technique in combination with lesion excision. Methods: Fifteen patients with 16 earlobe keloids were treated using a standard steroid injection protocol with Kenalog (Bristol-Myers Squibb, New York, NY), in combination with lesion excision. Strict follow-Lip was enforced, with repeat injections as needed at any sign of abnormal scar formation postoperatively. Results: Of 16 lesions, 15 (94%) were treated successfully with no sign of lesion recurrence at 6 months of follow-up. A single lesion was lost to follow-up and presented IS months postoperatively with recurrence. This lesion was subsequently retreated successfully. Conclusions: Kenalog injection in combination with excision is a well-tolerated and effective treatment of earlobe keloids in the pediatric population. We feel that timing of injection and adherence to a strict follow-up regimen is crucial to success. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:286 / 288
页数:3
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