Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer

被引:204
作者
Artale, Salvatore [1 ]
Sartore-Bianchi, Andrea [1 ]
Veronese, Silvio Marco [2 ]
Gambi, Valentina [1 ]
Sarnataro, Carolina Silvia [1 ]
Gambacorta, Marcello [2 ]
Lauricella, Calogero [2 ]
Siena, Salvatore [1 ]
机构
[1] Osped Niguarda Granda, Falck Div Med Oncol, Milan, Italy
[2] Osped Niguarda Granda, Div Pathol, Milan, Italy
关键词
D O I
10.1200/JCO.2008.18.7286
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:4217 / 4219
页数:4
相关论文
共 15 条
[1]  
Al-Mulla F, 1998, J PATHOL, V185, P130, DOI 10.1002/(SICI)1096-9896(199806)185:2<130::AID-PATH85>3.0.CO
[2]  
2-M
[3]   Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer [J].
Amado, Rafael G. ;
Wolf, Michael ;
Peeters, Marc ;
Van Cutsem, Eric ;
Siena, Salvatore ;
Freeman, Daniel J. ;
Juan, Todd ;
Sikorski, Robert ;
Suggs, Sid ;
Radinsky, Robert ;
Patterson, Scott D. ;
Chang, David D. .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (10) :1626-1634
[4]  
[Anonymous], 2008, Journal of Clinical Oncology
[5]   Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies [J].
Benvenuti, Silvia ;
Sartore-Bianchi, Andrea ;
Di Nicolantonio, Federica ;
Zanon, Carlo ;
Moroni, Mauro ;
Veronese, Silvio ;
Siena, Salvatore ;
Bardelli, Alberto .
CANCER RESEARCH, 2007, 67 (06) :2643-2648
[6]   Bleomycin in testicular cancer: Will pharmacogenomics improve treatment regimens? [J].
Bokemeyer, Carsten .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (11) :1783-1785
[7]   Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy [J].
Di Fiore, F. ;
Blanchard, F. ;
Charbonnier, F. ;
Le Pessot, F. ;
Lamy, A. ;
Galais, M. P. ;
Bastit, L. ;
Killian, A. ;
Sesboue, R. ;
Tuech, J. J. ;
Queuniet, A. M. ;
Paillot, B. ;
Sabourin, J. C. ;
Michot, F. ;
Michel, P. ;
Frebourg, T. .
BRITISH JOURNAL OF CANCER, 2007, 96 (08) :1166-1169
[8]  
European Medicines Agency, QUEST ANSW MARK AUTH
[9]   Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab [J].
Khambata-Ford, Shirin ;
Garrett, Christopher R. ;
Meropol, Neal J. ;
Basik, Mark ;
Harbison, Christopher T. ;
Wu, Shujian ;
Wong, Tai W. ;
Huang, Xin ;
Takimoto, Chris H. ;
Godwin, Andrew K. ;
Tan, Benjamin R. ;
Krishnamurthi, Smitha S. ;
Burris, Howard A., III ;
Poplin, Elizabeth A. ;
Hidalgo, Manuel ;
Baselga, Jose ;
Clark, Edwin A. ;
Mauro, David J. .
JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (22) :3230-3237
[10]   KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab [J].
Lievre, Astrid ;
Bachet, Jean-Baptiste ;
Boige, Valerie ;
Cayre, Anne ;
Le Corre, Delphine ;
Buc, Emmanuel ;
Ychou, Marc ;
Bouche, Olivier ;
Landi, Bruno ;
Louvet, Christophe ;
Andre, Thierry ;
Bibeau, Frederic ;
Diebold, Marie-Daniele ;
Rougier, Philippe ;
Ducreux, Michel ;
Tomasic, Gorana ;
Emile, Jean-Francois ;
Penault-Llorca, Frederique ;
Laurent-Puig, Pierre .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (03) :374-379