Genetic determinants of sports participation and daily physical activity

被引：110

作者：

Beunen, G ^{[1
]}

Thomis, M ^{[1
]}

机构：

[1] Katholieke Univ Leuven, Fac Phys Educ & Physiotherapy, Dept Kinesiol, B-3001 Louvain, Belgium

来源：

INTERNATIONAL JOURNAL OF OBESITY | 1999年 / 23卷 / Suppl 3期

关键词：

physical activity; resting metabolic rate; family and twin studies; heritability; genetic variation; environmental variation; linkage; sports participation; temperament;

D O I：

10.1038/sj.ijo.0800885

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVE: The purpose is to review the existing literature on genetic determinants of sports participation, daily physical activity (PA) resting metabolic rate (RMR) and activity as a temperamental trait. DESIGN: A synthesis will be given of the published material on this topic with special focus on twin and family data, and association and linkage studies. MEASUREMENTS: Self reported sports participation, daily PA, RMR and activity as a temperamental trait. ANALYSIS: Transmission and heritability coefficients calculated from twin and family data will be reported. RESULTS: The reported heritability coefficients for sports participation vary between 0.35 - 0.83, and those for daily PA between 0.29 - 0.62. If one of the parents or co-twins is active in sports, it is more likely that the child or co-twin is also active in sports (odds ratios (ORs) vary from 1.2 - 5.8). Twin and parent-child correlations for RMR also indicate a moderate genetic effect. At present, only a linkage between RMR and uncoupling protein 2 markers has been demonstrated. CONCLUSION: The genetic determination of sports participation, daily PA and RMR, varies from low to moderately high, and only between the uncoupling protein 2 genetic marker and RMR has a linkage has been demonstrated.

引用

页码：S55 / S63

页数：9

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