Biosynthetic studies of the alkaloid, stevensine, in a cell culture of the marine sponge Teichaxinella morchella

被引:74
作者
Andrade, P
Willoughby, R
Pomponi, SA [1 ]
Kerr, RG
机构
[1] Florida Atlantic Univ, Dept Chem & Biochem, Boca Raton, FL 33431 USA
[2] Florida Atlantic Univ, Ctr Mol Biosci & Biotechnol, Boca Raton, FL 33431 USA
[3] Harbor Branch Oceanog Inst Inc, Div Biomed Marine Res, Ft Pierce, FL 34946 USA
基金
美国海洋和大气管理局;
关键词
D O I
10.1016/S0040-4039(99)00881-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The biosynthetic origin of stevensine, a C11N5 sponge alkaloid, has been investigated using a cell culture composed of archaeocytes from the sponge Teichaxinella morchella (Porifera: Demospongiae: Axinellidae). Histidine and ornithine/proline were identified as amino acid building blocks of stevensine. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:4775 / 4778
页数:4
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