Bisphosphonic compounds .8. A facile and selective one-pot synthesis of P,P-dialkyl (dichloromethylene)bisphosphonate partial esters

被引：11

作者：

Vepsalainen, J ^{[1
]}

Nupponen, H ^{[1
]}

Pohjala, E ^{[1
]}

机构：

[1] LEIRAS OY,FIN-33721 TAMPERE,FINLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 20期

关键词：

D O I：

10.1016/0040-4039(96)00605-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparations of P,P-dialkyl partial esters of (dichloromethylene)bisphosphonic acid from readily available tetraesters with good selectivity and purity have been developed. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：3533 / 3536

页数：4

共 10 条

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[7] THE ROLE OF BISPHOSPHONATES IN THE PREVENTION AND TREATMENT OF OSTEOPOROSIS
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[8] BISPHOSPHONIC COMPOUNDS .5. SELECTIVE PREPARATION OF (DICHLOROMETHYLENE)BISPHOSPHONATE PARTIAL ESTERS
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POHJALA, E
[J]. TETRAHEDRON LETTERS, 1993, 34 (28) : 4551 - 4554
[9] BISPHOSPHONIC COMPOUNDS .3. PREPARATION AND IDENTIFICATION OF TETRAALKYL METHYLENEBISPHOSPHONATES AND (ALPHA-HALOMETHYLENE)BISPHOSPHONATES BY MASS-SPECTROMETRY, NMR-SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY
VEPSALAINEN, J
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[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1992, (05): : 835 - 842
[10] AN IMPROVED SYNTHETIC METHOD AND THE FIRST CRYSTAL-STRUCTURES FOR (DIHALOMETHYLENE)BISPHOSPHONATE PARTIAL ESTERS
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POHJALA, EK
[J]. TETRAHEDRON, 1995, 51 (24) : 6805 - 6818

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