Biological therapies for atrial fibrillation

被引：11

作者：

Amit, Guy ^{[1
]}

Qin, Hao ^{[1
]}

Donahue, J. Kevin ^{[1
]}

机构：

[1] Case Western Reserve Univ, Metrohlth Med Ctr, Heart & Vasc Res Ctr, Cleveland, OH 44109 USA

来源：

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY | 2008年 / 52卷 / 03期

关键词：

atrial fibrillation; arrhythmia; heart; gene therapy; cell therapy; atrioventricular node;

D O I：

10.1097/FJC.0b013e318182c8e0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atrial fibrillation is a prominent cause of morbidity and mortality in developed countries. Current treatment strategies center on controlling heart rate while allowing fibrillation to persist or targeting fibrillation primarily and attempting to maintain sinus rhythm. Pharmacological therapies are largely successful for rate control, although mild toxicities are common. Rhythm control strategies are often unsuccessful, leaving patients in atrial fibrillation despite attempts to maintain sinus rhythm. This review will discuss novel biological strategies that are currently under development and may eventually have impact on the management of atrial fibrillation.

引用

页码：222 / 227

页数：6

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