Electrohydrodynamic Jetting Behaviour of Polyhedral Oligomeric Silsesquioxane Nanocomposite

被引：18

作者：

Bakhshi, R. ^{[1
,2
]}

Edirisinghe, M. J. ^{[1
]}

Darbyshire, A. ^{[2
]}

Ahmad, Z. ^{[1
]}

Seifalian, A. M. ^{[2
]}

机构：

[1] UCL, Dept Mech Engn, London WC1E 7JE, England

[2] UCL, Acad Div Surg & Intervent Sci, Biomat & Tissue Engn Ctr, London NW3 2PF, England

来源：

JOURNAL OF BIOMATERIALS APPLICATIONS | 2009年 / 23卷 / 04期

基金：

英国工程与自然科学研究理事会;

关键词：

electrohydrodynamic spraying; stent; coating; nanocomposite; polymer; silsesquioxane; DRUG-ELUTING STENTS; ELECTROSTATIC SPRAY DEPOSITION; STEEL CORONARY STENTS; IN-VITRO; CARDIOVASCULAR STENTS; BIOMEDICAL APPLICATIONS; DIELECTRIC LIQUIDS; METALLIC STENTS; COATINGS; RELEASE;

D O I：

10.1177/0885328208089125

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In this paper, we investigate in detail the electrohydrodynamic spraying of a nonbiodegradable nanocomposite polyhedral oligomeric silsesquioxane polymer developed in our laboratories and currently being explored for coating metallic stent materials. Different concentrations of the polymer have been dissolved to prepare, characterise, and electrohydrodynamically deposit the polymer on stainless steel. From the experiments, the solution containing 15 wt% polymer was selected for further investigation. The variation of film/coating thickness as a function of spraying time was studied and the structural features of the film were assessed using microscopy. Films were also tensile tested. This study has identified a process and conditions which can be used in our stent coating research.

引用

页码：293 / 309

页数：17

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