Immunohistochemistry used as a screening method for persistent bovine viral diarrhea virus infection

被引：52

作者：

Brodersen, BW ^{[1
]}

机构：

[1] Univ Nebraska, Inst Agr & Nat Resources, Dept Vet & BIomed Sci, Nebraska Vet Diagnost Ctr, Lincoln, NE 68583 USA

来源：

VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE | 2004年 / 20卷 / 01期

关键词：

D O I：

10.1016/j.cvfa.2003.11.007

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Cattle persistently infected (PI) with bovine viral diarrhea virus (BVDV) are a major source of infection to herds. To successfully control BVDV, it is necessary to identify and cull those cattle PI with BVDV. Immunohistochemistry (IHC) is a useful tool for sensitive and specific detection of BVDV antigens in infected cattle. Skin of cattle PI with BVDV is one of the tissues where BVDV can be consistently identified by IHC and is readily accessible for sampling. Use of IHC on skin biopsies (in the form of ear notches) as a method to identify cattle PI with BVDV has resulted in a reliable. affordable technique for mass testing of cattle at an early age without maternal antibody interference. The ability to test large numbers of cattle to identify those PI with BVDV will enable implementation of programs for control and eventual eradication of BVDV.

引用

页码：85 / +

页数：10

共 37 条

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