Warts in a Cohort of Danish Kidney Transplanted Patients: Impact on Quality of Life

被引:12
作者
Zachariae, Claus [1 ]
Sand, Carsten [2 ]
Hansen, Jesper Melchior [3 ]
Sorensen, Soren Schwartz [4 ]
Koch, Karen [5 ]
Villumsen, John [6 ]
Axelsen, Mads [5 ]
机构
[1] Univ Copenhagen, Dept Dermatol, Gentofte Hosp, DK-2900 Hellerup, Denmark
[2] Univ Copenhagen, Dept Nephrol, Bispebjerg Hosp, DK-2900 Hellerup, Denmark
[3] Univ Copenhagen, Herlev Hosp, DK-2900 Hellerup, Denmark
[4] Univ Copenhagen, Rigshosp, DK-2900 Hellerup, Denmark
[5] Symbion Sci Pk, NatImmune AS, Copenhagen, Denmark
[6] Cyncron Biometr AS, Birkerod, Denmark
关键词
transplantation; warts; skin cancer; DLQI; INDEX;
D O I
10.2340/00015555-1377
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100227 [皮肤病学];
摘要
There are no published clinical studies evaluating the impact of warts on quality of life after transplantation. The aim of this study was to determine the frequency of self-reported skin warts and skin cancer and their impact on quality of life in kidney transplanted patients, as measured with the Dermatology Life Quality Index (DLQI). Of 740 patients with a functioning renal allograft and were free of dialysis who were surveyed, 568 returned the questionnaires. Patients were asked about general health issues, with a focus on transplantation history, cutaneous warts and whether they had ever had cutaneous cancer. A total of 285 (52%) patients replied that they had warts, and these increased with time since last transplantation, with a p-value <0.0001. A total of 101 patients (18%) reported that they had ever had skin cancer. The median DLQI was 0 for patients not having warts, 1 for patients with warts, and 2 for patients having warts and skin cancer. In conclusion, renal transplant recipients experience increasing numbers of warts and skin cancer over time, and having skin cancer impairs patients' quality of life to a greater degree than warts.
引用
收藏
页码:615 / 618
页数:4
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