Cloning and expression of class a β-lactamase gene in blaABPS Burkholderia pseudomallei

被引：31

作者：

Cheung, TKM ^{[1
]}

Ho, PL ^{[1
]}

Woo, PCY ^{[1
]}

Yuen, KY ^{[1
]}

Chau, PY ^{[1
]}

机构：

[1] Univ Hong Kong, Dept Microbiol, Queen Mary Hosp, Pokfulam, Hong Kong, Peoples R China

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 04期

关键词：

D O I：

10.1128/AAC.46.4.1132-1135.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The beta-lactamase gene bla(BPS) in Burkholderia pseudomallei was cloned and expressed in Escherichia coli. BPS-1 is a cephalosporinase with an isoelectrie point of 7.7. Sequence analysis of BPS-1 revealed conserved motifs typical of class A beta-lactamases and a relationship to the PenA (in B. cepacia) and BlaI (in Yersinia enterocolitica) lineages.

引用

页码：1132 / 1135

页数：4

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