Advances in analytical technologies to evaluate the quality of traditional Chinese medicines

被引:50
作者
Jing, Jing [1 ]
Ren, Wei Chao [2 ]
Chen, Si Bao [3 ,4 ,5 ]
Wei, Ming [2 ]
Parekh, Harendra S. [1 ]
机构
[1] Univ Queensland, Ctr Excellence, Sch Pharm & Pharm Australia, Wolloongabba, Qld 4072, Australia
[2] Griffith Univ, Griffith Inst Hlth & Med Res, Southport, Qld 4222, Australia
[3] Hong Kong Polytech Univ, State Key Lab Chinese Med & Mol Pharmacol, Shenzhen 518057, Peoples R China
[4] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China
[5] Peking Union Med Coll, Beijing 100193, Peoples R China
关键词
Analytical instrumentation; Chemical fingerprinting; Chinese herbal medicine; Chromatographic fingerprinting; High-performance liquid chromatography (HPLC); Liquid chromatography coupled to mass spectrometry (LC/MS); Multi-component mixture; Traditional Chinese medicine (TCM); Two-dimensional liquid chromatography (2DLC); Ultra-performance liquid chromatography (UPLC); TIME-OF-FLIGHT; 2-DIMENSIONAL LIQUID-CHROMATOGRAPHY; TANDEM MASS-SPECTROMETRY; FINGERPRINTING ANALYSIS; RADIX-SCROPHULARIAE; IDENTIFICATION; UPLC; GLYCOSIDES; DERIVATIVES; VALIDATION;
D O I
10.1016/j.trac.2012.11.006
中图分类号
O65 [分析化学];
学科分类号
070302 [分析化学];
摘要
Traditional Chinese medicines (TCMs) are in widespread use around the world, increasingly so in western nations as the complementary therapy of choice. Nonetheless, quality and safety of TCMs remain key concerns, hindering their wider popularity among the international healthcare fraternity. Cutting-edge analytical technologies are urgently required to address these concerns, ensuring reproducible identification and verification of constituents within any given TCM. Recent improvements in engineering advanced analytical instrumentation with improved sensitivity and precision to allow greater resolution of multi-component mixtures are driving the quality-control standards of TCMs towards universally-acceptable standards. We review recent applications of key analytical techniques in quality assurance and authentication of herbs and their extracts. We highlight the emerging role of chemical fingerprinting of TCMs and the latest regulatory requirements imposed on Chinese herbal medicines utilizing chromatographic fingerprinting. (c) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:39 / 45
页数:7
相关论文
共 42 条
[1]
[Anonymous], HONG KONG CHIN MED M
[2]
Identification of polyoxypregnane glycosides from the stems of Marsdenia tenacissima by high-performance liquid chromatography/tandem mass spectrometry [J].
Chen, Juanjuan ;
Li, Xiaoyu ;
Sun, Cuirong ;
Pan, Yuanjiang ;
Schlunegger, Urs Peter .
TALANTA, 2008, 77 (01) :152-159
[3]
Rapid identification of oleanane-type saponins in the roots of Stephanotis mucronata by liquid chromatography/electrospray tandem mass spectrometry [J].
Chen, Juanjuan ;
Ye, Yiping ;
Sun, Cuirong ;
Pan, Yuanjiang .
ANALYTICA CHIMICA ACTA, 2008, 613 (01) :74-82
[4]
Quality control of Schizonepeta tenuifolia Briq by solid-phase microextraction gas chromatography/mass spectrometry and principal component analysis [J].
Chun, Mi-Hee ;
Kim, Eun Kyung ;
Lee, Kang Ro ;
Jung, Jee H. ;
Hong, Jongki .
MICROCHEMICAL JOURNAL, 2010, 95 (01) :25-31
[5]
Simultaneous characterization of quaternary alkaloids, 8-oxoprotoberberine alkaloids, and a steroid compound in Coscinium fenestratum by liquid chromatography hybrid ion trap time-of-flight mass spectrometry [J].
Deevanhxay, Phengxay ;
Suzuki, Makoto ;
Maeshibu, Nariaki ;
Li, He ;
Tanaka, Ken ;
Hirose, Sachio .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2009, 50 (03) :413-425
[6]
Review - Mass spectrometry and protein analysis [J].
Domon, B ;
Aebersold, R .
SCIENCE, 2006, 312 (5771) :212-217
[7]
Study on the destructive effect to inherent quality of Fritillaria thunbergii Miq. (Zhebeimu) by sulfur-fumigated process using chromatographic fingerprinting analysis [J].
Duan, Baozhong ;
Huang, Linfang ;
Chen, Shilin .
PHYTOMEDICINE, 2012, 19 (06) :562-568
[8]
Exact-mass library for pesticides using a molecular-feature database [J].
Ferrer, Imma ;
Fernandez-Alba, Amadeo ;
Zweigenbaum, Jerry A. ;
Thurman, E. Michael .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2006, 20 (24) :3659-3668
[9]
Comprehensive liquid chromatography: Fundamental aspects and practical considerations-A review [J].
Francois, Isabelle ;
Sandra, Koen ;
Sandra, Pat .
ANALYTICA CHIMICA ACTA, 2009, 641 (1-2) :14-31
[10]
Selective comprehensive multidimensional separation for resolution enhancement in high performance liquid chromatography. Part II: Applications [J].
Groskreutz, Stephen R. ;
Swenson, Michael M. ;
Secor, Laura B. ;
Stoll, Dwight R. .
JOURNAL OF CHROMATOGRAPHY A, 2012, 1228 :41-50