IGF-1R is overexpressed in poor-prognostic subtypes of multiple myeloma

被引：53

作者：

Chng, WJ ^{[1
]}

Gualberto, A

Fonseca, R

机构：

[1] Mayo Clin Scottsdale, Div Hematol Oncol, Scottsdale, AZ 85259 USA

[2] Pfizer Global Res & Dev, New London, CT USA

来源：

LEUKEMIA | 2006年 / 20卷 / 01期

关键词：

D O I：

10.1038/sj.leu.2403997

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

引用

收藏

页码：174 / 176

页数：3

相关论文

共 9 条

[1]

Bataille R, 2005, HAEMATOLOGICA, V90, P706

[2]

Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma [J].

Bergsagel, PL ;

Kuehl, WM ;

Zhan, FH ;

Sawyer, J ;

Barlogie, B ;

Shaughnessy, J .

BLOOD, 2005, 106 (01) :296-303

[3]

The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma [J].

Fonseca, R ;

Debes-Marun, CS ;

Picken, EB ;

Dewald, GW ;

Bryant, SC ;

Winkler, JM ;

Blood, E ;

Oken, MM ;

Santana-Dávila, R ;

González-Paz, N ;

Kyle, RA ;

Gertz, MA ;

Dispenzieri, A ;

Lacy, MQ ;

Greipp, PR .

BLOOD, 2003, 102 (07) :2562-2567

[4]

Insulin-like growth factor I is a growth and survival factor in human multiple myeloma cell lines [J].

GeorgiiHemming, P ;

Wiklund, HJ ;

Ljunggren, O ;

Nilsson, K .

BLOOD, 1996, 88 (06) :2250-2258

[5]

Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors [J].

Mitsiades, CS ;

Mitsiades, NS ;

McMullan, CJ ;

Poulaki, V ;

Shringarpure, R ;

Akiyama, M ;

Hideshima, T ;

Chauhan, D ;

Joseph, M ;

Libermann, TA ;

García-Echeverría, C ;

Pearson, MA ;

Hofmann, F ;

Anderson, KC ;

Kung, AL .

CANCER CELL, 2004, 5 (03) :221-230

[6]

Insulin-like growth factors and neoplasia [J].

Pollak, MN ;

Schernhammer, ES ;

Hankinson, SE .

NATURE REVIEWS CANCER, 2004, 4 (07) :505-518

[7]

Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with total therapy I: interpretation in the context of global gene expression [J].

Shaughnessy, J ;

Jacobson, J ;

Sawyer, J ;

McCoy, J ;

Fassas, A ;

Zhan, FH ;

Bumm, K ;

Epstein, J ;

Anaissie, E ;

Jagannath, S ;

Vesole, D ;

Siegel, D ;

Desikan, R ;

Munshi, N ;

Badros, A ;

Tian, EM ;

Zangari, M ;

Tricot, G ;

Crowley, J ;

Barlogie, B .

BLOOD, 2003, 101 (10) :3849-3856

[8]

Serum insulinlike growth factor is not elevated in patients with multiple myeloma but is still a prognostic factor [J].

Standal, T ;

Borset, M ;

Lenhoff, S ;

Wisloff, F ;

Stordal, B ;

Sundan, A ;

Waage, A ;

Seidel, C .

BLOOD, 2002, 100 (12) :3925-3929

[9]

Tai YT, 2003, CANCER RES, V63, P5850