Characterization of dendrimers

被引:207
作者
Caminade, AM [1 ]
Laurent, R [1 ]
Majoral, JP [1 ]
机构
[1] CNRS, Chim Coordinat Lab, F-31077 Toulouse 4, France
关键词
dendrimers; NMR; mass spectrometry; microscopy; fluorescence; scattering techniques; rheology;
D O I
10.1016/j.addr.2005.09.011
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Dendrimers pertain both to the molecular chemistry world for their step by step controlled syntheses, and to the polymer world because of their repetitive structure made of monomers; thus they benefit from analytical techniques from both worlds. This review is a survey of the main analytical techniques used for the characterization of the chemical composition, the morphology, the shape, and the homogeneity of dendrimers. It includes NMR, IR, Raman, UV-Visible, fluorescence, circular dichroism, X-ray diffraction, mass spectrometry, SAXS, SANS, Laser Light Scattering, microscopy, SEC, EPR, electrochemistry, electrophoresis, intrinsic viscosity, DSC, and dielectric spectroscopy. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:2130 / 2146
页数:17
相关论文
共 203 条
[1]  
ACHAR S, 1994, ANGEW CHEM INT EDIT, V33, P847, DOI 10.1002/anie.199408471
[2]   SIZE AND SOLUTION PROPERTIES OF GLOBULAR TERT-BUTYLOXYCARBONYL-POLY(ALPHA,XI-L-LYSINE) [J].
AHARONI, SM ;
CROSBY, CR ;
WALSH, EK .
MACROMOLECULES, 1982, 15 (04) :1093-1098
[3]   Self-assembly of [n]rotaxanes bearing dendritic stoppers [J].
Amabilino, DB ;
Ashton, PR ;
Balzani, V ;
Brown, CL ;
Credi, A ;
Frechet, JMJ ;
Leon, JW ;
Raymo, FM ;
Spencer, N ;
Stoddart, JF ;
Venturi, M .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (48) :12012-12020
[4]  
[Anonymous], 2001, DENDRIMERS OTHER DEN
[5]  
Archut A, 1998, CHEM-EUR J, V4, P699, DOI 10.1002/(SICI)1521-3765(19980416)4:4<699::AID-CHEM699>3.0.CO
[6]  
2-9
[7]   Photophysical properties of pyrene-functionalized poly(propylene imine) dendrimers [J].
Baker, LA ;
Crooks, RM .
MACROMOLECULES, 2000, 33 (24) :9034-9039
[8]   Versatile peptide dendrimers for nucleic acid delivery [J].
Bayele, HK ;
Sakthivel, T ;
O'Donell, M ;
Pasi, KJ ;
Wilderspin, AF ;
Lee, CA ;
Toth, I ;
Florence, AT .
JOURNAL OF PHARMACEUTICAL SCIENCES, 2005, 94 (02) :446-457
[9]  
Benito M, 2002, EUR J INORG CHEM, P2477
[10]   MALDI TOF mass spectrometry for the characterization of phosphorus-containing dendrimers. Scope and limitations [J].
Blais, JC ;
Turrin, CO ;
Caminade, AM ;
Majoral, JP .
ANALYTICAL CHEMISTRY, 2000, 72 (20) :5097-5105