Cyclic trimer of 5-(aminomethyl)-2-furancarboxylic acid as a novel synthetic receptor for carboxylate recognition

被引：38

作者：

Chakraborty, TK ^{[1
]}

Tapadar, S ^{[1
]}

Kumar, SK ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 07期

关键词：

cyclic peptides; furan amino acid; synthetic receptors; molecular recognition;

D O I：

10.1016/S0040-4039(01)02367-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel 18-membered cyclic oligopeptide 1 based on 5-(aminomethyl)-2-furancarboxylic acid (2), is developed as an excellent receptor for carboxylate binding having an association constant of 8.64x10(3) M-1 for tetrabutylammonium acetate in CD3CN. The synthesis of 1 was achieved by a high-yielding cyclotrimerization reaction of the unfunctionalized furan amino acid 2. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1317 / 1320

页数：4

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