Coffee drinking and endometrial cancer risk: a metaanalysis of observational studies

被引：42

作者：

Bravi, Francesca ^{[1
,2
]}

Scotti, Lorenza ^{[3
]}

Bosetti, Cristina

Gallus, Silvano

Negri, Eva

La Vecchia, Carlo ^{[2
]}

Tavani, Alessandra

机构：

[1] Ist Ric Farmacol Mario Negri, Dipartimento Epidemiol, I-20156 Milan, Italy

[2] Univ Milan, Ist Stat Med & Biometria GA Maccacaro, Milan, Italy

[3] Univ Milano Bicocca, Dipartimento Stat, Milan, Italy

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2009年 / 200卷 / 02期

关键词：

coffee; endometrial cancer; metaanalysis; risk factor; PHYSICAL-ACTIVITY; DIETARY FACTORS; CIGARETTE-SMOKING; CONSUMPTION; CAFFEINE; TEA; PLASMA; BIAS;

D O I：

10.1016/j.ajog.2008.10.032

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

We conducted a metaanalysis of published studies on the relation between coffee drinking and endometrial cancer risk, which included 2 cohort (201 cases) and 7 case-control studies (2409 cases). The summary relative risk (RR) for coffee drinkers vs nondrinkers was 0.80 (95% confidence interval [CI], 0.68-0.94), with significant heterogeneity between studies. Compared with nondrinkers, the summary RR was 0.87 (95% CI, 0.78-0.97) for low-to-moderate coffee drinkers and 0.64 (95% CI, 0.48-0.86) for heavy coffee drinkers. The summary RR for an increase of 1 cup/d was 0.93 (95% CI, 0.89-0.97), which suggests an inverse relation between coffee and endometrial cancer. However, the causality must be confirmed.

引用

页码：130 / 135

页数：6

共 44 条

[1]

[Anonymous], 1993, CAFFEINE COFFEE HLTH

[2] THE ANTIESTROGENIC EFFECT OF CIGARETTE-SMOKING IN WOMEN [J].

BARON, JA ;

LAVECCHIA, C ;

LEVI, F .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1990, 162 (02) :502-514

[3]

BRAVI F, 2008, AM J OBSTET IN PRESS

[4] Coffee drinking and hepatocellular carcinoma risk: A meta-analysis [J].

Bravi, Francesca ;

Bosetti, Cristina ;

Tavani, Alessandra ;

Bagnardi, Vincenzo ;

Gallus, Silvano ;

Negri, Eva ;

Franceschi, Silvia ;

La Vecchia, Carlo .

HEPATOLOGY, 2007, 46 (02) :430-435

[5] REPRODUCTIVE, MENSTRUAL, AND MEDICAL RISK-FACTORS FOR ENDOMETRIAL CANCER - RESULTS FROM A CASE-CONTROL STUDY [J].

BRINTON, LA ;

BERMAN, ML ;

MORTEL, R ;

TWIGGS, LB ;

BARRETT, RJ ;

WILBANKS, GD ;

LANNOM, L ;

HOOVER, RN .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1992, 167 (05) :1317-1325

[6] Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity [J].

Cavin, C ;

Holzhaeuser, D ;

Scharf, G ;

Constable, A ;

Huber, WW ;

Schilter, B .

FOOD AND CHEMICAL TOXICOLOGY, 2002, 40 (08) :1155-1163

[7]

Cook LS., 2006, CANC EPIDEMIOLOGY PR, VThird, P1027

[8] Reliability of information on cigarette smoking and beverage consumption provided by hospital controls [J].

DAvanzo, B ;

LaVecchia, C ;

Katsouyanni, K ;

Negri, E ;

Trichopoulos, D .

EPIDEMIOLOGY, 1996, 7 (03) :312-315

[9]

de Sotillo DVR, 2002, J NUTR BIOCHEM, V13, P717, DOI 10.1016/S0955-2863(02)00231-0

[10] METAANALYSIS IN CLINICAL-TRIALS [J].

DERSIMONIAN, R ;

LAIRD, N .

CONTROLLED CLINICAL TRIALS, 1986, 7 (03) :177-188

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