Products from microwave and ultrasonic wave assisted acid hydrolysis of chitin

被引：70

作者：

Ajavakom, Anawat ^{[1
]}

Supsvetson, Sulaleewan ^{[2
]}

Somboot, Aimjit ^{[2
]}

Sukwattanasinitt, Mongkol ^{[1
]}

机构：

[1] Chulalongkorn Univ, Fac Sci, Dept Chem, Bangkok 10330, Thailand

[2] Chulalongkorn Univ, Fac Sci, Program Petrochem & Polymer Sci, Bangkok 10330, Thailand

来源：

CARBOHYDRATE POLYMERS | 2012年 / 90卷 / 01期

关键词：

Chitin; Chitosan; Glucosamine; Hydrolysis; Microwave chemistry; Sonochemistry; GLUCOSAMINE SULFATE; 2-ACETAMIDO-2-DEOXY-D-GLUCOSE;

D O I：

10.1016/j.carbpol.2012.04.064

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Hydrolysis of alpha-chitin in concentrated hydrochloric acid under elevated temperature is a general preparation of a nutrapharmaceutical glucosamine hydrochloride (GlcN.HCl). In this study, the microwave and ultrasonic wave assisted acid hydrolysis of shrimp shell alpha-chitin are investigated with an aim to improve the reaction rate and selectivity. Microwave heating shortens the hydrolysis time from 120 min in the conventional heating process to 12 min to afford GlcN.HCl in 57% yield. Sonication can be used to assist chitin dissolution in 38% HCl prior to the hydrolysis at 120 degrees C for 120 min to produce GlcN.HCl in 62% yield. The selective hydrolysis of glycosidic bond of chitin is achievable at 30 degrees C for 4h to give N-acetyl glucosamine (GlcNAc) in 37% yield. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：73 / 77

页数：5

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