Fluoroquinolone resistance in Ureaplasma parvum in the United States

被引:25
作者
Duffy, L
Glass, J
Hall, G
Avery, R
Rackley, R
Peterson, S
Waites, K
机构
[1] Univ Alabama, Dept Pathol, Birmingham, AL 35226 USA
[2] Inst Genom Res, Rockville, MD USA
[3] J Craig Venter Inst, Rockville, MD USA
[4] Cleveland Clin Fdn, Cleveland, OH 44195 USA
关键词
D O I
10.1128/JCM.44.4.1590-1591.2006
中图分类号
Q93 [微生物学];
学科分类号
071005 [微生物学]; 100705 [微生物与生化药学];
摘要
We report the first case of naturally occurring fluoroquinolone resistance in Ureaplasma spp. from the United States. Resistance in this case probably developed as a result of mutations in the gyrA and parC genes of the DNA gyrase/topoisomerase IV complex that occurred in the presence of antimicrobial selective pressure.
引用
收藏
页码:1590 / 1591
页数:2
相关论文
共 15 条
[1]
In vitro activity of trovafloxacin compared to those of five antimicrobials against mycoplasmas including Mycoplasma hominis and Ureaplasma urealyticum fluoroquinolone-resistant isolates that have been genetically characterized [J].
Bebear, CM ;
Renaudin, H ;
Charron, A ;
Gruson, D ;
Lefrancois, M ;
Bebear, C .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (09) :2557-2560
[2]
DNA gyrase and topoisomerase IV mutations in clinical isolates of Ureaplasma spp. and Mycoplasma hominis resistant to fluoroquinolones [J].
Bébéar, CM ;
Renaudin, H ;
Charron, A ;
Clerc, M ;
Pereyre, S ;
Bébéar, C .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (10) :3323-3325
[3]
SUBOPTIMAL EFFICACY OF ERYTHROMYCIN AND TETRACYCLINE AGAINST VAGINAL UREAPLASMA UREALYTICUM [J].
BOWIE, WR ;
WILLETTS, V .
SEXUALLY TRANSMITTED DISEASES, 1987, 14 (02) :88-91
[4]
Disruption of gene mg218 of Mycoplasma genitalium through homologous recombination leads to an adherence-deficient phenotype [J].
Dhandayuthapani, S ;
Rasmussen, WG ;
Baseman, JB .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (09) :5227-5232
[5]
Peptide methionine sulfoxide reductase (MsrA) is a virulence determinant in Mycoplasma genitalium [J].
Dhandayuthapani, S ;
Blaylock, MW ;
Bebear, CM ;
Rasmussen, WG ;
Baseman, JB .
JOURNAL OF BACTERIOLOGY, 2001, 183 (19) :5645-5650
[6]
DNA gyrase, topoisomerase IV, and the 4-quinolones [J].
Drlica, K ;
Zhao, XL .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1997, 61 (03) :377-+
[7]
BACTERIURIA DUE TO UREAPLASMAS AND OTHER FASTIDIOUS ORGANISMS DURING PREGNANCY - PREVALENCE AND SIGNIFICANCE [J].
GILBERT, GL ;
GARLAND, SM ;
FAIRLEY, KF ;
MCDOWALL, DMR .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1986, 5 (06) :S239-S243
[8]
The complete sequence of the mucosal pathogen Ureaplasma urealyticum [J].
Glass, JI ;
Lefkowitz, EJ ;
Glass, JS ;
Heiner, CR ;
Chen, EY ;
Cassell, GH .
NATURE, 2000, 407 (6805) :757-762
[9]
Characterization of ureaplasmas isolated from preterm infants with and without bronchopulmonary dysplasia [J].
Katz, B ;
Patel, P ;
Duffy, L ;
Schelonka, RL ;
Dimmitt, RA ;
Waites, KB .
JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (09) :4852-4854
[10]
UREAPLASMA UREALYTICUM IN PATIENTS WITH ACUTE SYMPTOMS OF URINARY-TRACT INFECTION [J].
MCDONALD, MI ;
LAM, MH ;
BIRCH, DF ;
DARCY, AF ;
FAIRLEY, KF ;
PAVILLARD, ERJ ;
KUNIN, CM .
JOURNAL OF UROLOGY, 1982, 128 (03) :517-519