Transbronchial Cryobiopsies for the Diagnosis of Diffuse Parenchymal Lung Diseases: Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure

被引：293

作者：

Hetzel, Juergen ^{[1
]}

Maldonado, Fabien ^{[2
]}

Ravaglia, Claudia ^{[3
]}

Wells, Athol U. ^{[4
]}

Colby, Thomas V. ^{[5
]}

Tomassetti, Sara ^{[3
]}

Ryu, Jay H. ^{[6
]}

Fruchter, Oren ^{[7
,8
]}

Piciucchi, Sara ^{[9
]}

Dubini, Alessandra ^{[10
]}

Cavazza, Alberto ^{[11
]}

Chilosi, Marco ^{[12
]}

Sverzellati, Nicola ^{[13
]}

Valeyre, Dominique ^{[14
]}

Leduc, Dimitri ^{[15
]}

Walsh, Simon L. F. ^{[16
]}

Gasparini, Stefano ^{[17
,18
]}

Hetzel, Martin ^{[19
]}

Hagmeyer, Lars ^{[20
]}

Haentschel, Maik ^{[1
]}

Eberhardt, Ralf ^{[21
]}

Darwiche, Kaid ^{[22
]}

Yarmus, Lonny B. ^{[23
]}

Torrego, Alfonso ^{[24
]}

Krishna, Ganesh ^{[25
]}

Shah, Pallav L. ^{[26
,27
]}

Annema, Jouke T. ^{[28
]}

Herth, Felix J. F. ^{[21
]}

Poletti, Venerino ^{[3
,29
]}

机构：

[1] Univ Tubingen, Dept Hematol Oncol Rheumatol Immunol & Pulmonol, Otfried Muller Str 10, DE-72076 Tubingen, Germany

[2] Vanderbilt Univ, Div Pulm & Crit Care, 221 Kirkland Hall, Nashville, TN 37235 USA

[3] Osped GB Morgagni, Dept Dis Thorax, Via Carlo Forlanini,34 Pavil Morgagni, IT-47100 Forli, Italy

[4] Royal Brompton Hosp, Interstitial Lung Dis Unit, London, England

[5] Mayo Clin, Dept Pathol, Scottsdale, AZ USA

[6] Mayo Clin, Pulm & Crit Care Med, Rochester, MN USA

[7] Wolfson Med Ctr, Pulm Div, Tel Aviv, Israel

[8] Tel Aviv Univ, Tel Aviv, Israel

[9] Osped GB Morgagni, Dept Radiol, Forli, Italy

[10] Osped GB Morgagni, Dept Pathol, Forli, Italy

[11] S Maria Nuova Hosp IRCCS, Dept Pathol, Reggio Emilia, Italy

[12] Verona Univ, Dept Pathol, Verona, Italy

[13] Univ Parma, Div Radiol, Dept Clin Sci, Parma, Italy

[14] Avicenne Univ Hosp, AP HP, Bobigny, France

[15] Free Univ Brussels, Erasme Univ Hosp, Dept Chest Med, Brussels, Belgium

[16] Kings Coll Hosp Fdn Trust, London, England

[17] Univ Politecn Marche, Dept Biomed Sci & Publ Hlth, Ancona, Italy

[18] Azienda Osped Univ Osped Riuniti, Pulm Dis Unit, Dept Internal Med, Ancona, Italy

[19] Krankenhaus Roten Kreuz, Stuttgart, Germany

[20] Bethanien Hosp, Ctr Sleep Med & Resp Care, Clin Pneumol & Allergol, Solingen, Germany

[21] Heidelberg Univ, Dept Pneumol & Crit Care Med, Translat Lung Res Ctr Heidelberg, German Ctr Lung Res DZL,Thoraxklin, Heidelberg, Germany

[22] Univ Duisburg Essen, Univ Hosp, Dept Intervent Pulmonol, Ruhrlandklin, Essen, Germany

[23] Johns Hopkins Univ, Sch Med, Baltimore, MD USA

[24] Univ Hosp Santa Creu & St Pau, Resp Dept, Bronchoscopy Unit, Barcelona, Spain

[25] Univ Calif San Francisco, El Camino Hosp, Div Pulm Crit Care Allergy & Sleep Med, San Francisco, CA 94143 USA

[26] Royal Brompton & Harefield NHS Fdn Trust, Resp Biomed Res Unit, Natl Inst Hlth Res, London, England

[27] Imperial Coll, London, England

[28] Acad Med Ctr, Dept Resp Med, Amsterdam, Netherlands

[29] Aarhus Univ Hosp, Dept Resp Dis & Allergol, Aarhus, Denmark

来源：

RESPIRATION | 2018年 / 95卷 / 03期

关键词：

Transbronchial lung cryobiopsy; Diffuse parenchymal lung disease; Interstitial lung disease; Safety; Bronchoscopy; IDIOPATHIC PULMONARY-FIBROSIS; SUPRAGLOTTIC AIRWAY DEVICE; ACUTE EXACERBATIONS; SINGLE INSTITUTION; BIOPSY; YIELD; EXPERIENCE; EFFICACY; TRIAL; TRANSPLANTATION;

D O I：

10.1159/000484055

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

100201 [内科学];

摘要：

Transbronchial cryobiopsies (TBCB) have recently been introduced as a promising and safer alternative to surgical lung biopsy in the diagnostic approach to diffuse parenchymal lung diseases (DPLD). Despite a substantial and expanding body of literature, the technique has not yet been standardized and its place in the diagnostic algorithm of DPLD remains to be defined. In part, this reflects concerns over the diagnostic yield and safety of the procedure, together with the rapid spread of the technique without competency and safety standards; furthermore, there is a substantial procedural variability among centers and interventional pulmonologists. We report this expert statement proposed during the third international conference on "Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Disease" (Ravenna, October 27-28, 2016), which formulates evidence-and expert-based suggestions on the indications, contraindications, patient selection, and procedural aspects of the procedure. The following 5 domains were reviewed: (1) what is the role of TBCB in the diagnostic evaluation of DPLD: patient selection; (2) pathological considerations; (3) contraindications and safety considerations; (4) how should TBCB be performed and in what procedural environment; and (5) who should perform TBCB. Finally, the existence of white paper recommendations may also reassure local hospital credentialing committees tasked with endorsing an adoption of the technique. (C) 2018 S. Karger AG, Basel

引用

页码：188 / 200

页数：13

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