High frequency of mutations of the PIK3CA gene in human cancers

被引：3073

作者：

Samuels, Y

Wang, ZH

Bardelli, A

Silliman, N

Ptak, J

Szabo, S

Yan, H

Gazdar, A

Powell, DM

Riggins, GJ

Willson, JKV

Markowitz, S

Kinzler, KW

Vogelstein, B

Velculescu, VE ^{[1
]}

机构：

[1] Johns Hopkins Univ, Inst Med, Howard Hughes Med Inst, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD 21231 USA

[2] Duke Univ, Med Ctr, Dept Pathol, Durham, NC 27710 USA

[3] Univ Texas, SW Med Ctr, Hamon Ctr Therapeut Oncol Res, Dallas, TX 75390 USA

[4] Univ Texas, SW Med Ctr, Dept Pathol, Dallas, TX 75390 USA

[5] Univ Virginia Hlth Syst, Div Gastroenterol Hepatol, Charlottesville, VA 22908 USA

[6] Univ Hosp Cleveland, Ireland Canc Ctr, Howard Hughes Med Inst, Cleveland, OH 44106 USA

[7] Case Western Reserve Univ, Cleveland, OH 44106 USA

来源：

SCIENCE | 2004年 / 304卷 / 5670期

关键词：

D O I：

10.1126/science.1096502

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

[No abstract available]

引用

页码：554 / 554

页数：1

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