CRRT efficiency and efficacy in relation to solute size

被引：30

作者：

Clark, WR

Ronco, C

机构：

[1] Baxter Healthcare Corp, Div Renal, McGaw Pk, IL USA

[2] Indiana Univ, Sch Med, Div Nephrol, Indianapolis, IN USA

[3] Osped San Bartolo, Div Nephrol, Vicenza, Italy

来源：

KIDNEY INTERNATIONAL | 1999年 / 56卷

关键词：

solute; clearance; diffusion; convection; membrane; hemofiltration;

D O I：

10.1046/j.1523-1755.56.s72.18.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Removal of blood solutes in patients with decreased or absent glomerular filtration is the prime objective of continuous renal replacement therapies (CRRTs). However, because these blood solutes are of different molecular weights, factors such as the porosity and hydrophobicity of the filter membranes and the extracorporeal flow rates determine the CRRT that is the most effective filtration system. This article discusses both small and large solute removal, the interaction of convection and diffusion, and the potential for CRRTs to remove particular inflammatory mediators of acute renal failure.

引用

页码：S3 / S7

页数：5

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