Complete assignment of 1H and 13C NMR data of pravastatin derivatives

被引:7
作者
Bacher, Markus [1 ]
Baumann, Karl [1 ]
Knapp, Hermann [1 ]
Steck, Andrea [1 ]
Teibl, Sigrid [1 ]
机构
[1] Novartis Inst BioMed Res, A-1235 Vienna, Austria
关键词
statins; pravastatin; H-1; NMR; C-13; FUNCTION-ASSOCIATED ANTIGEN-1; CONFORMATIONAL-CHANGES; ML-236B COMPACTIN; INHIBITION; STATINS;
D O I
10.1002/mrc.2312
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
The complete H-1 and C-13 NMR data of 27 pravastatin derivatives are presented. Assignment was achieved by use of 1 D and 2D NMR experiments (selective 1D NOE, COSY, NOESY, HSQC, HMBC). Copyright (C) 2008 John Wiley & Sons, Ltd.
引用
收藏
页码:71 / 83
页数:13
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