Antibiotic selection pressure and resistance in Streptococcus pneumoniae and Streptococcus pyogenes

被引:284
作者
Albrich, WC
Monnet, DL
Harbarth, S
机构
[1] Univ Hosp Geneva, Infect Control Program, CH-1211 Geneva 14, Switzerland
[2] Statens Serum Inst, DK-2300 Copenhagen, Denmark
[3] Emory Univ, Sch Med, Atlanta, GA USA
关键词
D O I
10.3201/eid1003.030252
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We correlated outpatient antibiotic use with prevalence of penicillin-nonsusceptible Streptococcus pneumoniae (PNSP), macrolide-resistant S. pneumoniae (MRSP), and macrolide-resistant S. pyogenes (MRGAS) in 20 countries. Total antibiotic use was correlated with PNSP (r = 0.75; p < 0.001), as was macrolide use with MRSP (r = 0.88; p < 0.001) and MRGAS (r = 0.71; p = 0.004). Streptococcal resistance is directly associated with antibiotic selection pressure on a national level.
引用
收藏
页码:514 / 517
页数:4
相关论文
共 36 条
[1]   Assessment of the susceptibility of Streptococcus pneumoniae to cefaclor and loracarbef in 13 countries [J].
Bandak, SI ;
Turnak, MR ;
Allen, BS ;
Bolzon, LD ;
Preston, DA .
JOURNAL OF CHEMOTHERAPY, 2000, 12 (04) :299-305
[2]   Antibiotic usage in Nordic countries [J].
Bergan, T .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2001, 18 (03) :279-282
[3]   A European study on the relationship between antimicrobial use and antimicrobial resistance [J].
Bronzwaer, SLAM ;
Cars, O ;
Buchholz, U ;
Mölstad, S ;
Goettsch, W ;
Veldhuijzen, IK ;
Kool, JL ;
Sprenger, MJW ;
Degener, JE .
EMERGING INFECTIOUS DISEASES, 2002, 8 (03) :278-282
[4]   Antimicrobial resistance amongst isolates of Streptococcus pyogenes and Staphylococcus aureus in the PROTEKT antimicrobial surveillance programme during 1999-2000 [J].
Cantón, R ;
Loza, E ;
Morosini, MI ;
Baquero, F .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2002, 50 :9-24
[5]   Variation in antibiotic use in the European Union [J].
Cars, O ;
Mölstad, S ;
Melander, A .
LANCET, 2001, 357 (9271) :1851-1853
[6]   Decreased susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada [J].
Chen, DK ;
McGeer, A ;
de Azavedo, JC ;
Low, DE .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (04) :233-239
[7]   Antimicrobial resistance of invasive Streptococcus pneumoniae in Slovenia front 1997 to 2000 [J].
Cizman, M ;
Pokorn, M ;
Paragi, M .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2002, 49 (03) :582-584
[8]   The relationship between trends in macrolide use and resistance to macrolides of common respiratory pathogens [J].
Cizman, M ;
Pokorn, M ;
Seme, K ;
Orazem, A ;
Paragi, M .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2001, 47 (04) :475-477
[9]   Antibiotic use and resistance of Streptococcus pneumoniae in The Netherlands during the period 1994-1999 [J].
de Neeling, AJ ;
Overbeek, BP ;
Horrevorts, AM ;
Ligtvoet, EEJ ;
Goettsch, WG .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2001, 48 (03) :441-444
[10]   Macrolide resistance and erythromycin resistance determinants among Belgian Streptococcus pyogenes and Streptococcus pneumoniae isolates [J].
Descheemaeker, P ;
Chapelle, S ;
Lammens, C ;
Hauchecorne, M ;
Wijdooghe, M ;
Vandamme, P ;
Ieven, M ;
Goossens, H .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 45 (02) :167-173