The International Serious Adverse Events Consortium (iSAEC) phenotype standardization project for drug-induced torsades de pointes

被引：20

作者：

Behr, Elijah R. ^{[1
]}

January, Craig ^{[2
]}

Schulze-Bahr, Eric ^{[3
]}

Grace, Andrew A. ^{[4
]}

Kaeaeb, Stefan ^{[5
]}

Fiszman, Monica ^{[6
]}

Gathers, Shaniece ^{[7
]}

Buckman, ShaAvhree ^{[8
]}

Youssef, Ashraf ^{[9
]}

Pirmohamed, Munir ^{[10
]}

Roden, Dan ^{[11
]}

机构：

[1] St Georges Univ London, Cardiovasc Res Ctr, London SW17 0RE, England

[2] Univ Wisconsin, Madison, WI USA

[3] Univ Hosp, Inst Genet Heart Dis, Dept Cardiol & Angiol, Munster, Germany

[4] Univ Cambridge, Cambridge, England

[5] Ludwig Maximilians Univ Hosp Munich, Dept Med 1, Munich, Germany

[6] US FDA, Div Cardiovasc & Renal Prod, CDER, Silver Spring, MD USA

[7] US FDA, Off Translat Sci, CDER, Silver Spring, MD USA

[8] US FDA, Silver Spring, MD USA

[9] Takeda Global R&D Ctr, Deerfield, IL USA

[10] Univ Liverpool, Inst Translat Med, Liverpool L69 3BX, Merseyside, England

[11] Vanderbilt Univ, Med Ctr, Sch Med, Oates Inst Expt Therapeut, Nashville, TN 37232 USA

来源：

EUROPEAN HEART JOURNAL | 2013年 / 34卷 / 26期

基金：

英国惠康基金;

关键词：

LONG-QT SYNDROME; CLINICAL-FEATURES; PROLONGATION; ARRHYTHMIA; QUINIDINE; INJURY; KCNE1; SCN5A; RISK; GENE;

D O I：

10.1093/eurheartj/ehs172

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

[No abstract available]

引用

页码：1958 / 1963

页数：6

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