Detection of α-L fucose containing carbohydrates in mouse immature olfactory neurons

被引:8
作者
Ducray, A [1 ]
Propper, A [1 ]
Kastner, A [1 ]
机构
[1] Univ Franche Comte, Neurosci Lab, EA 1063, F-25030 Besancon, France
关键词
olfactory epithelium; olfactory neurons; lectins; Ulex europaeus agglutinin-I; Tetragonolobus purpureas agglutinin; Dolichos biflorus; glycoconjugates;
D O I
10.1016/S0304-3940(99)00674-6
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The cellular location of alpha-L fucose was studied in mice olfactory epithelium (OE) using the Ulex europaeus agglutinin-I (UEA-I) and Tetragonolobus purpureas agglutinin (TPA), In adult mice, UEA-I a nd TPA revealed a layer of cells that mostly correspond to immature olfactory neurons. Moreover, autoradiographic studies after H-3-T incorporation showed that UEA-I cell labelling occurred during the week following the division of neural cell precursors. In newborn animals, active neurogenesis process is associated with a higher number of UEA-I labelled cells, Olfactory neurogenesis may thus involve a transient event of protein fucosylation, preceding axonal growth. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:17 / 20
页数:4
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