Aptamers as recognition elements for label-free analytical devices

被引：92

作者：

de-los-Santos-Alvarez, Noemi ^{[1
]}

Jesus Lobo-Castanon, Maria ^{[1
]}

Miranda-Ordieres, Arturo J. ^{[1
]}

Tunon-Blanco, Paulino ^{[1
]}

机构：

[1] Univ Oviedo, Dept Quim Fis & Analit, Oviedo 33006, Spain

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2008年 / 27卷 / 05期

关键词：

acoustic wave; aptamer; aptasensor; electrochemistry; impedance; label-free; mass spectrometry; microcantilever; optical device; SPR; surface-plasmon resonance;

D O I：

10.1016/j.trac.2008.03.003

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In spite of the impressive advances in aptasensing, the search for label-free devices for the detection of the aptamer-ligand interaction is still a challenge. This review highlights the advantages and the limitations of using label-free detection strategies and summarizes the state of the art in this field. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：437 / 446

页数：10

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