Restoring GABAergic Signaling and Neuronal Synchrony in Schizophrenia

被引:9
作者
Akbarian, Schahram [1 ]
机构
[1] Univ Massachusetts, Sch Med, Brudnick Neuropsychiat Res Inst, Worcester, MA 01604 USA
关键词
D O I
10.1176/appi.ajp.2008.08081225
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
引用
收藏
页码:1507 / 1509
页数:3
相关论文
共 10 条
[1]   Altered Expression of Genes Involved in GABAergic Transmission and Neuromodulation of Granule Cell Activity in the Cerebellum of Schizophrenia Patients [J].
Bullock, W. Michael ;
Cardon, Karen ;
Bustillo, Juan ;
Roberts, Rosalinda C. ;
Perrone-Bizzozero, Nora I. .
AMERICAN JOURNAL OF PSYCHIATRY, 2008, 165 (12) :1594-1603
[2]  
FATEMI SH, 2008, CEREBELLUM 0404
[3]   Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior [J].
Fuchs, Elke C. ;
Zivkovic, Aleksandar R. ;
Cunningham, Mark O. ;
Middleton, Steven ;
LeBeau, Fiona E. N. ;
Bannerman, David M. ;
Rozov, Andrei ;
Whittington, Miles A. ;
Traub, Roger D. ;
Rawlins, J. Nicholas P. ;
Monyer, Hannah .
NEURON, 2007, 53 (04) :591-604
[4]   GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon [J].
Guidotti, A ;
Auta, J ;
Davis, JM ;
Dong, EB ;
Grayson, DR ;
Veldic, M ;
Zhang, XQ ;
Costa, E .
PSYCHOPHARMACOLOGY, 2005, 180 (02) :191-205
[5]   Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters [J].
Huang, Hsien-Sung ;
Matevossian, Anouch ;
Whittle, Catheryne ;
Kim, Se Young ;
Schumacher, Armin ;
Baker, Stephen P. ;
Akbarian, Schahram .
JOURNAL OF NEUROSCIENCE, 2007, 27 (42) :11254-11262
[6]   Subunit-Selective Modulation of GABA Type A Receptor Neurotransmission and Cognition in Schizophrenia [J].
Lewis, David A. ;
Cho, Raymond Y. ;
Carter, Cameron S. ;
Eklund, Kevin ;
Forster, Sarah ;
Kelly, Mary Ann ;
Montrose, Debra .
AMERICAN JOURNAL OF PSYCHIATRY, 2008, 165 (12) :1585-1593
[7]   Effects of γ-aminobutyric acid-modulating drugs on working memory and brain function in patients with schizophrenia [J].
Menzies, Lara ;
Ooi, Cinly ;
Kamath, Shri ;
Suckling, John ;
McKenna, Peter ;
Fletcher, Paul ;
Bullmore, Edward T. ;
Stephenson, Caroline .
ARCHIVES OF GENERAL PSYCHIATRY, 2007, 64 (02) :156-167
[8]   The primate cortico-cerebellar system: anatomy and function [J].
Ramnani, Narender .
NATURE REVIEWS NEUROSCIENCE, 2006, 7 (07) :511-522
[9]   DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons [J].
Siegmund, Kimberly D. ;
Connor, Caroline M. ;
Campan, Mihaela ;
Long, Tiffany I. ;
Weisenberger, Daniel J. ;
Biniszkiewicz, Detlev ;
Jaenisch, Rudolf ;
Laird, Peter W. ;
Akbarian, Schahram .
PLOS ONE, 2007, 2 (09)
[10]   The role of oscillations and synchrony in cortical networks and their putative relevance for the pathophysiology of schizophrenia [J].
Uhlhaas, Peter J. ;
Haenschel, Corinna ;
Nikolic, Danko ;
Singer, Wolf .
SCHIZOPHRENIA BULLETIN, 2008, 34 (05) :927-943