Polymer-supported triphenylphosphine-ditriflate: a novel dehydrating reagent

被引：33

作者：

Elson, KE

Jenkins, ID ^{[1
]}

Loughlin, WA

机构：

[1] Griffith Univ, Nat Prod Discovery, Brisbane, Qld 4111, Australia

[2] Griffith Univ, Sch Sci, Brisbane, Qld 4111, Australia

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 12期

关键词：

solid-phase reagent; dehydration; peptide coupling; azide; Mitsunobu;

D O I：

10.1016/j.tetlet.2004.02.018

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new type of polymeric dehydrating reagent, readily prepared by the treatment of polymer-supported triphenylphosphine oxide with triflic anhydride, was found to be effective in a variety of dehydration reactions such as ester and amide formation; the polymer-supported triphenylphosphine oxide was easily recovered and reused several times without the loss of activity. (C) 2004 Elsevier Ltd. All rights reserved.

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页码：2491 / 2493

页数：3

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