Toxic epidermal necrolysis induced by nevirapine therapy: Description of two cases and review of the literature

被引：13

作者：

Cattelan, AM

Trevenzoli, M

Sasset, L

Sgarabotto, D

Lanzafame, M

Meneghetti, F

机构：

[1] Azienda Osped Padova, Div Infect Dis, I-35100 Padua, Italy

[2] Univ Verona, ULSS Veneto 14, I-37100 Verona, Italy

[3] Univ Verona, Div Infect Dis, I-37100 Verona, Italy

来源：

JOURNAL OF INFECTION | 2001年 / 43卷 / 04期

关键词：

D O I：

10.1053/jinf.2001.0902

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We describe two cases of toxic epidermal necrolysis developed during an antiretroviral therapy regimen containing nevirapine. It seems likely that the poor adherence to the dose escalation regimen of nevirapine has caused this life-threatening disease. A complete and written information on the scheduled antiretroviral therapy is mandatory, above all for individuals coming from developing countries where language barriers have not yet been successfully overcome. (C) 2001 The British Infection Society.

引用

页码：246 / 249

页数：4

共 27 条

[1] TOXIC EPIDERMAL NECROLYSIS - A REVIEW [J].

AVAKIAN, R ;

FLOWERS, FP ;

ARAUJO, OE ;

RAMOSCARO, FA .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1991, 25 (01) :69-79

[2] CLINICAL CLASSIFICATION OF CASES OF TOXIC EPIDERMAL NECROLYSIS, STEVENS-JOHNSON SYNDROME, AND ERYTHEMA MULTIFORME [J].

BASTUJIGARIN, S ;

RZANY, B ;

STERN, RS ;

SHEAR, NH ;

NALDI, L ;

ROUJEAU, JC .

ARCHIVES OF DERMATOLOGY, 1993, 129 (01) :92-96

[3] Sex differences in nevirapine rash [J].

Bersoff-Matcha, SJ ;

Miller, WC ;

Aberg, JA ;

van der Horst, C ;

Hamrick, HJ ;

Powderly, WG ;

Mundy, LM .

CLINICAL INFECTIOUS DISEASES, 2001, 32 (01) :124-129

[4] A controlled trial of nevirapine plus zidovudine versus zidovudine alone in p24 antigenaemic HIV-infected patients [J].

Carr, A ;

Vella, S ;

deJong, MD ;

Sorice, F ;

Imrie, A ;

Boucher, CA ;

Cooper, DA .

AIDS, 1996, 10 (06) :635-641

[5]

Carr A, 1996, ADV EXP MED BIOL, V394, P299

[6] Severe hepatic failure related to nevirapine treatment [J].

Cattelan, AM ;

Erne, E ;

Salatino, A ;

Trevenzoli, M ;

Carretta, G ;

Meneghetti, F ;

Cadrobbi, P .

CLINICAL INFECTIOUS DISEASES, 1999, 29 (02) :455-456

[7] Plasmapheresis in toxic epidermal necrolysis [J].

Chaidemenos, GC ;

Chrysomallis, F ;

Sombolos, K ;

Mourellou, O ;

Ioannides, D ;

Papakonstantinou, M .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 1997, 36 (03) :218-221

[8]

CHEESEMAN SH, 1995, J ACQ IMMUN DEF SYND, V8, P141

[9] Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection - A randomized, double-blind, placebo-controlled trial [J].

DAquila, RT ;

Hughes, MD ;

Johnson, VA ;

Fischl, MA ;

Sommadossi, JP ;

Liou, SH ;

Timpone, J ;

Myers, M ;

Basgoz, N ;

Niu, M ;

Hirsch, MS ;

Costanzo, L ;

Ruben, S ;

Berzins, B ;

Martinez, A ;

Fishman, I ;

Kazial, K ;

Cort, SN ;

Robinson, P ;

Hall, D ;

Macy, H ;

McLaren, C ;

Rooney, J ;

Warwick, J ;

CavailleColl, M ;

Valentine, F ;

Booth, D ;

Soeiro, R ;

Stein, D ;

Zingman, B ;

Schliosberg, J ;

Polsky, B ;

Sepkowitz, K ;

Sharpe, V ;

Giordano, M ;

Wanke, C ;

Gulick, R ;

Craven, D ;

Grodman, C ;

Fife, K ;

Black, J ;

Todd, K ;

Nixon, H ;

Sperber, K ;

Gerits, P ;

Mildvan, D ;

Nicholas, P ;

Murphy, RL ;

Kessler, H ;

Pulvirenti, J .

ANNALS OF INTERNAL MEDICINE, 1996, 124 (12) :1019-1030

[10]

Engelhardt S. L., 1997, Journal of Burn Care and Rehabilitation, V18, P520, DOI 10.1097/00004630-199711000-00009

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