Steroidal saponins from the tuber of Ophiopogon japonicus

被引:26
作者
Zhang, Tao [1 ,2 ]
Kang, Li-Ping [1 ,3 ]
Yu, He-Shui [1 ,3 ]
Liu, Yi-Xun [1 ]
Zhao, Yang [1 ]
Xiong, Cheng-Qi [1 ]
Zhang, Jie [1 ,3 ]
Zou, Peng [1 ]
Song, Xin-Bo [3 ]
Liu, Chao [1 ]
Ma, Bai-Ping [1 ]
机构
[1] Beijing Inst Radiat Med, Beijing 100850, Peoples R China
[2] Beijing Univ Technol, Beijing 100124, Peoples R China
[3] Tianjin Univ Tradit Chinese Med, Tianjin 300193, Peoples R China
关键词
Ophiopogon japonicus; Steroidal saponins; Ophiopogonins H-O; Structural identification; THUNB; KER-GAWL; NMR-SPECTROSCOPY; STRUCTURAL ELUCIDATION; FUROSTANOL SAPONINS; GLYCOSIDES; CONSTITUENTS; SAPOGENINS; RHIZOMES; ROOTS;
D O I
10.1016/j.steroids.2012.04.015
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Eight novel steroidal saponins, ophiopogonins H-O (1-8), along with seven known steroidal saponins (9-15) were isolated from the tubers of Ophiopogon japonicus. The structures of these new compounds were determined by detailed spectroscopic analysis, including extensive 1D and 2D NMR data, and the analysis of hydrolytic reaction products. For the first time, rare furostanol saponins with disaccharide moiety linked at position C-26 of the aglycone were reported to be isolated from a natural source. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码:1298 / 1305
页数:8
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