Injectable bone substitute using a hydrophilic polymer

被引：66

作者：

Weiss, P ^{[1
]}

Gauthier, O ^{[1
]}

Bouler, JM ^{[1
]}

Grimandi, G ^{[1
]}

Daculsi, G ^{[1
]}

机构：

[1] Fac Chirurg Dent, UFR Odontol, Equipe INSERM Mat Interet Biol, UPRES EA 2159, F-44042 Nantes 01, France

来源：

BONE | 1999年 / 25卷 / 02期

关键词：

biomaterial; calcium phosphate; injection; bone substitute;

D O I：

10.1016/S8756-3282(99)00146-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We studied a new injectable biomaterial for bone and dental surgery consisting of a hydrophilic polymer as matrix and bioactive calcium phosphate (CaP ceramics as fillers. This material is composed of complex fluids whose flow is determined by the laws of rheology. We investigated the macromolecular effects on this composite in a tube, The stability of the polymer and the mixture is essential to the production of a ready-to-use injectable biomaterial, These flow properties are necessary to obtain Cap bioactivity in a dental canal or bone defect during percutaneous surgery. Macromolecules provide spaces between CaP ceramic granules and facilitate the role of the biological agents of bone substitution. (Bone 25:67S-70S; 1999) (C) 1999 by Elsevier Science Inc. All rights reserved.

引用

页码：67S / 70S

页数：4

共 21 条

[1] SKELETAL REPAIR BY IN-SITU FORMATION OF THE MINERAL PHASE OF BONE [J].