Extrinsic allergic alveolitis

被引：30

作者：

Ismail, T

Mcsharry, C

Boyd, G

机构：

[1] Univ Teknologi MARA, Fac Med, Shah Alam 40450, Selangor Dural, Malaysia

[2] N Glasgow Univ Hosp, NHS Trust, Glasgow, Lanark, Scotland

来源：

RESPIROLOGY | 2006年 / 11卷 / 03期

关键词：

cytokines; extrinsic allergic alveolitis; hypersensitivity pneumonitis; immunopathogenesis;

D O I：

10.1111/j.1440-1843.2006.00839.x

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Extrinsic allergic alveolitis (also known as hypersensitivity pneumonitis) is caused by repeated inhalation of mainly organic antigens by sensitized subjects. This induces a hypersensitivity response in the distal bronchioles and alveoli and subjects may present clinically with a variety of symptoms. The aims of this review are to describe the current concepts of the immunological response, the diverse clinical presentation of this disease, the relevant investigations and management, and areas for future studies.

引用

页码：262 / 268

页数：7

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[1] Blockade of CD40-CD40 ligand interactions protects against radiation-induced pulmonary inflammation and fibrosis [J].