Right lobe living: Donor liver transplantation

被引:314
作者
Marcos, A
Fisher, RA
Ham, JM
Shiffman, ML
Sanyal, AJ
Luketic, VAC
Sterling, RK
Posner, MP
机构
[1] Med Coll Virginia, Div Transplantat, Dept Surg, Richmond, VA 23298 USA
[2] Med Coll Virginia, Dept Med, Div Gastroenterol, Sect Hepatol & Liver Transplantat, Richmond, VA 23298 USA
关键词
D O I
10.1097/00007890-199909270-00012
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background, The shortage of livers for transplantation has prompted transplant centers to seek alternatives to conventional cadaveric liver transplantation, Left lateral segmentectomy from living donors has proven to be a safe operation for the donor with excellent results in the pediatric population. Left lobectomy, conceived to supply more tissue, still provides insufficient liver mass for an average size adult patient. Right lobectomy could supply a graft of adequate size. Methods. Donors were considered only after recipients were listed according to United Network for Organ Sharing (UNOS) criteria. Donor evaluation included liver biopsy, magnetic resonance imaging, and celiac and mesenteric angiography. The donor operation consisted of a light lobectomy uniformly performed throughout the series as described herein. Results. Twenty-five right lobe living donor liver transplants were performed between adults, with no significant complications in donors. Recipient and graft survival was 88%, with three recipient deaths secondary to uncontrolled sepsis in patients at high risk for liver transplant; all three had functioning grafts. Conclusions. Right lohe living donor liver transplantation poses challenges that require a meticulous surgical technique to minimize morbidity in the recipient. Right lobectomies for living donation can be performed safely with minimal risk to both donor and recipient although providing adequate liver mass for an average size adult patient.
引用
收藏
页码:798 / 803
页数:6
相关论文
共 16 条
  • [1] LIVER-TRANSPLANTATION IN CHILDREN FROM LIVING RELATED DONORS - SURGICAL TECHNIQUES AND RESULTS
    BROELSCH, CE
    WHITINGTON, PF
    EMOND, JC
    HEFFRON, TG
    THISTLETHWAITE, JR
    STEVENS, L
    PIPER, J
    WHITINGTON, SH
    LICHTOR, JL
    [J]. ANNALS OF SURGERY, 1991, 214 (04) : 428 - 439
  • [2] COUINAUD C, 1991, CONTROLLED PARTITION, P15
  • [3] In situ splitting of the cadaveric liver for transplantation
    Goss, JA
    Yersiz, H
    Shackleton, CR
    Seu, P
    Smith, CV
    Markowitz, JS
    Farmer, DG
    Ghobrial, RM
    Markmann, JF
    Arnaout, WS
    Imagawa, DK
    Colquhoun, SD
    Fraiman, MH
    McDiarmid, SV
    Busuttil, RW
    [J]. TRANSPLANTATION, 1997, 64 (06) : 871 - 877
  • [4] Complications in 100 living-liver donors
    Grewal, HP
    Thistlethwaite, JR
    Loss, GE
    Fisher, JS
    Cronin, DC
    Siegel, CT
    Newell, KA
    Bruce, DS
    Woodle, ES
    Brady, L
    Kelly, S
    Boone, P
    Oswald, K
    Millis, JM
    [J]. ANNALS OF SURGERY, 1998, 228 (02) : 214 - 219
  • [5] HEFFRON TG, 1994, TRANSPLANT P, V26, P144
  • [6] Huang TL, 1996, TRANSPLANT P, V28, P1669
  • [7] Ikai I, 1996, TRANSPLANT P, V28, P56
  • [8] Living related liver transplantation in adults
    Kawasaki, S
    Makuuchi, M
    Matsunami, H
    Hashikura, Y
    Ikegami, T
    Nakazawa, Y
    Chisuwa, H
    Terada, M
    Miyagawa, S
    [J]. ANNALS OF SURGERY, 1998, 227 (02) : 269 - 274
  • [9] Adult-to-adult living donor liver transplantation using extended right lobe grafts
    Lo, CM
    Fan, ST
    Liu, CL
    Wei, WI
    Lo, RJW
    Lai, CL
    Chan, JKF
    Ng, IOL
    Fung, A
    Wong, J
    [J]. ANNALS OF SURGERY, 1997, 226 (03) : 261 - 269
  • [10] MarcosAlvarez A, 1996, ARCH SURG-CHICAGO, V131, P292