Typing of clinical herpes simplex virus type 1 and type 2 isolates with monoclonal antibodies

被引：25

作者：

Liljeqvist, JÅ ^{[1
]}

Svennerholm, B ^{[1
]}

Bergström, T ^{[1
]}

机构：

[1] Gothenburg Univ, Dept Virol, S-41346 Gothenburg, Sweden

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1999年 / 37卷 / 08期

关键词：

D O I：

10.1128/JCM.37.8.2717-2718.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The purpose of this study was to evaluate the performance of a herpes simplex virus (HSV) type 1-specific anti-glycoprotein C-1 monoclonal antibody (MAb) and a type 2-spetific anti-glycoprotein G-2 MAb for typing of 2,400 clinical HSV-1 isolates and 2,400 clinical HSV-2 isolates, respectively, using an enzyme immunoassay. The anti-HSV-1 MAb showed sensitivity and specificity of 100%, and the anti-HSV-2 MAb showed a sensitivity of 99.46% and 100% specificity, indicating that these MAbs are suitable for typing of clinical HSV isolates.

引用

页码：2717 / 2718

页数：2

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