The burden of inflammatory bowel disease in Europe

被引:856
作者
Burisch, Johan [1 ]
Jess, Tine [2 ]
Martinato, Matteo [3 ]
Lakatos, Peter L. [4 ]
机构
[1] Herlev Univ Hosp, Med Sect, Ctr Digest Dis, Copenhagen, Denmark
[2] Natl Ctr Hlth Data & Dis Control, Statens Serum Inst, Dept Epidemiol Res, Copenhagen, Denmark
[3] Univ Padua, Dept Surg Oncol & Gastroenterol Sci, I-35100 Padua, Italy
[4] Semmelweis Univ, Dept Med 1, H-1083 Budapest, Hungary
关键词
Inflammatory bowel disease; Incidence; Mortality; Surgery; Disability; Economy; POPULATION-BASED COHORT; CAUSE-SPECIFIC MORTALITY; QUALITY-OF-LIFE; REGIONAL PATIENT GROUP; CROHNS-DISEASE; ULCERATIVE-COLITIS; FOLLOW-UP; COLORECTAL-CANCER; COPENHAGEN COUNTY; INCEPTION COHORT;
D O I
10.1016/j.crohns.2013.01.010
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
Inflammatory bowel diseases (IBD) are chronic disabling gastrointestinal disorders impacting every aspect of the affected individual's life and account for substantial costs to the health care system and society. New epidemiological data suggest that the incidence and prevalence of the diseases are increasing and medical therapy and disease management have changed significantly in the last decade. An estimated 2.5-3 million people in Europe are affected by IBD, with a direct healthcare cost of 4.6-5.6 bn Euros/year. Therefore, the aim of this review is to describe the burden of IBD in Europe by discussing the latest epidemiological data, the disease course and risk for surgery and hospitalization, mortality and cancer risks, as well as the economic aspects, patients disability and work impairment. (c) 2013 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:322 / 337
页数:16
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