Myelodysplasia occurring after fludarabine treatment for chronic lymphocytic leukaemia

被引：16

作者：

Frewin, RJ ^{[1
]}

Provan, D ^{[1
]}

Smith, AG ^{[1
]}

机构：

[1] ROYAL S HANTS HOSP,DEPT HAEMATOL,NHS TRUST,SOUTHAMPTON SO14 0YG,HANTS,ENGLAND

来源：

CLINICAL AND LABORATORY HAEMATOLOGY | 1997年 / 19卷 / 02期

关键词：

fludarabine; chronic lymphocytic leukaemia; myelodysplasia;

D O I：

10.1046/j.1365-2257.1997.00229.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The purine analogue, fludarabine, is of proven efficacy in the treatment of lymphoid malignancies. The drug appears to be well tolerated with minimal side-effects, and few toxicities have been observed, A case of myelodysplasia occurring after therapy with fludarabine is presented and its implications are discussed.

引用

页码：151 / 152

页数：2

共 10 条

[1]

BOLDT DH, 1984, CANCER RES, V44, P4661

[2] IMMUNOLOGICAL ABNORMALITIES IN MYELODYSPLASTIC SYNDROMES .2. COEXISTENT LYMPHOID OR PLASMA-CELL NEOPLASMS - A REPORT OF 20 CASES UNRELATED TO CHEMOTHERAPY [J].

COPPLESTONE, JA ;

MUFTI, GJ ;

HAMBLIN, TJ ;

OSCIER, DG .

BRITISH JOURNAL OF HAEMATOLOGY, 1986, 63 (01) :149-159

[3]

GREVER MR, 1986, BLOOD S, V68, pA223

[4]

KEATING MJ, 1989, BLOOD, V74, P19

[5]

ROBERTSON LE, 1994, LEUKEMIA, V8, P2047

[6] MULTIPLE-MYELOMA TERMINATING IN ACUTE-LEUKEMIA - REPORT OF 12 CASES AND REVIEW OF LITERATURE [J].

ROSNER, F ;

GRUNWALD, H .

AMERICAN JOURNAL OF MEDICINE, 1974, 57 (06) :927-939

[7]

SCHLAIFER D, 1994, NOUV REV FR HEMATOL, V36, P341

[8]

SMITH AG, 1982, Q J MED, V51, P227

[9]

WIJERMANS PW, 1993, EUR J HAEMATOL, V50, P292

[10] THE ROLE OF FLUDARABINE IN HEMATOLOGICAL MALIGNANCIES [J].

WRIGHT, SJ ;

ROBERTSON, LE ;

OBRIEN, S ;

PLUNKETT, W ;

KEATING, MJ .

BLOOD REVIEWS, 1994, 8 (03) :125-134

← 1 →