Discovery of a pseudo β barrel:: Synthesis and formation by tiling of ferrocene cyclopeptides

被引：43

作者：

Chowdhury, S

Sanders, DAR

Schatte, G

Kraatz, HB

机构：

[1] Univ Saskatchewan, Dept Chem, Saskatoon, SK S7N 5C9, Canada

[2] Univ Saskatchewan, Saskatchewan Struct Sci Ctr, Saskatoon, SK S7N 5C9, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 05期

关键词：

beta barrel; ferrocene; macrocycles; peptides; self-assembly;

D O I：

10.1002/anie.200502788

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Self-assembly of 1,n′-disubstituted ferrocene cyclopeptides leads to the first model of β barrels, a ubiquitous structural motif in proteins. The β-barrel model has eight β strands arranged almost parallel to the axis of the channel with an internal pore diameter of 8 Å. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：751 / 754

页数：4

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