Biodegradable block copolymers

被引：249

作者：

Kumar, N

Ravikumar, MNV

Domb, AJ ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Dept Med Chem & Nat Prod, IL-91120 Jerusalem, Israel

[2] Univ Kentucky, Med Ctr, Dept Prevent Med & Environm Hlth, Lexington, KY 40536 USA

来源：

ADVANCED DRUG DELIVERY REVIEWS | 2001年 / 53卷 / 01期

关键词：

biodegradable; block copolymer; star-block copolymer; poly(esters); poly(ether-b-ester); poly(ether ester amide); surface modification; micelles; hydrogels; nanoparticles; microparticles; drug-targeting;

D O I：

10.1016/S0169-409X(01)00219-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Recently, block copolymers have got tremendous impetus on the ongoing research in the area of drug delivery technology, due to their capability to provide a biomaterial having a broad range of amphiphilic characteristics, as well as targeting the drugs to specific site. This article is an attempt to review applications of block copolymers in surface modification, drug targeting, nano and microparticles, hydrogels, micelles etc. The physicochemical properties of block copolymers and various synthetic routes for block copolymers are also discussed. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：23 / 44

页数：22

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