Pathophysiology of Campylobacter jejuni infections of humans

被引：152

作者：

Wassenaar, TM

Blaser, MJ

机构：

[1] Vanderbilt Univ, Sch Med, Div Infect Dis, Nashville, TN 37232 USA

[2] Vet Adm Med Ctr, Nashville, TN 37232 USA

[3] Univ Mainz, Inst Med Microbiol & Hyg, D-55101 Mainz, Germany

来源：

MICROBES AND INFECTION | 1999年 / 1卷 / 12期

关键词：

Campylobacter; microbial pathogenesis; bacterial toxins; enteric diseases; emerging infections;

D O I：

10.1016/S1286-4579(99)80520-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Campylobacter jejuni and closely related organisms are major causes of human bacterial enteritis. These infections can lead to extraintestinal disease and severe long-term complications. Of these, neurological damage, apparently due to the immune response of the host, is the most striking. This review examines current knowledge of the pathophysiology of the organism. Diversity of C. jejuni isolates in genotypic and phenotypic characteristics now is recognized and clinically relevant examples are presented. Expected future directions are outlined. (C) 1999 Editions scientifiques et medicales Elsevier SAS.

引用

页码：1023 / 1033

页数：11

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