Microtiter plate assays for inhibition of human, drug-metabolizing cytochromes P450

被引：370

作者：

Crespi, CL

Miller, VP

Penman, BW

机构：

[1] GENTEST Corporation, Woburn, MA 01801

来源：

ANALYTICAL BIOCHEMISTRY | 1997年 / 248卷 / 01期

关键词：

D O I：

10.1006/abio.1997.2145

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：188 / 190

页数：3

共 13 条

[1] KETOCONAZOLE AND SULFAPHENAZOLE AS THE RESPECTIVE SELECTIVE INHIBITORS OF P4503A AND 2C9
BALDWIN, SJ
BLOOMER, JC
SMITH, GJ
AYRTON, AD
CLARKE, SE
CHENERY, RJ
[J]. XENOBIOTICA, 1995, 25 (03) : 261 - 270
[2] BURKE MD, 1983, CHEM-BIOL INTERACT, V45, P243
[3] A MICROASSAY FOR MEASURING CYTOCHROME-P450IA1 AND CYTOCHROME-P450IIB1 ACTIVITIES IN INTACT HUMAN AND RAT HEPATOCYTES CULTURED ON 96-WELL PLATES
DONATO, MT
GOMEZLECHON, MJ
CASTELL, JV
[J]. ANALYTICAL BIOCHEMISTRY, 1993, 213 (01) : 29 - 33
[4] SIMULTANEOUS MEASUREMENT OF CYTOCHROME P4501A CATALYTIC ACTIVITY AND TOTAL PROTEIN-CONCENTRATION WITH A FLUORESCENCE PLATE READER
KENNEDY, SW
JONES, SP
[J]. ANALYTICAL BIOCHEMISTRY, 1994, 222 (01) : 217 - 223
[5] ISOFORM-SELECTIVE MECHANISM-BASED INHIBITION OF HUMAN CYTOCHROME-P450 1A2 BY FURAFYLLINE
KUNZE, KL
TRAGER, WF
[J]. CHEMICAL RESEARCH IN TOXICOLOGY, 1993, 6 (05) : 649 - 656
[6] P450-ENZYMES - INHIBITION MECHANISMS, GENETIC-REGULATION AND EFFECTS OF LIVER-DISEASE
MURRAY, M
[J]. CLINICAL PHARMACOKINETICS, 1992, 23 (02) : 132 - 146
[7] Specificity of substrate and inhibitor probes for cytochrome P450s: Evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes
Ono, S
Hatanaka, T
Hotta, H
Satoh, T
Gonzalez, FJ
Tsutsui, M
[J]. XENOBIOTICA, 1996, 26 (07) : 681 - 693
[8] An overview of current cytochrome P450 technology for assessing the safety and efficacy of new materials
Parkinson, A
[J]. TOXICOLOGIC PATHOLOGY, 1996, 24 (01) : 45 - 57
[9] UNDERSTANDING CONSEQUENCES OF CONCURRENT THERAPIES
PECK, CC
TEMPLE, R
COLLINS, JM
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1993, 269 (12): : 1550 - 1552
[10] HYDROXYLATION OF WARFARIN BY HUMAN CDNA-EXPRESSED CYTOCHROME-P-450 - A ROLE FOR P-4502C9 IN THE ETIOLOGY OF (S)-WARFARIN DRUG-INTERACTIONS
RETTIE, AE
KORZEKWA, KR
KUNZE, KL
LAWRENCE, RF
EDDY, AC
AOYAMA, T
GELBOIN, HV
GONZALEZ, FJ
TRAGER, WF
[J]. CHEMICAL RESEARCH IN TOXICOLOGY, 1992, 5 (01) : 54 - 59

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