Eprosartan - A review of its use in the management of hypertension

Sources: Medical literature published in any language since 1980 on eprosartan, identified using MEDLINE and EMBASE, supplemented by AdisBase (a proprietary database of Adis International). Additional references were identified from the reference lists of published articles. Bibliographical information, including contributory unpublished data, was also requested from the company developing the drug. Search strategy: MEDLINE search terms were 'eprosartan' or 'SKF-108566' and ('hypertension' or 'antihypertensive'). EMBASE and AdisBase search terms were 'eprosartan' and ('hypertension' or 'antihypertensive'). Searches were last updated 15 October 2005. Selection: Studies in patients with hypertension who received eprosartan. Inclusion of studies was based mainly on the methods section of the trials. When available, large, well controlled trials with appropriate statistical methodology were preferred. Relevant pharmacodynamic and pharmacokinetic data are also included.