A consistent relationship between local white matter architecture and functional specialisation in medial frontal cortex

被引：41

作者：

Behrens, TEJ ^{[1
]}

Jenkinson, M ^{[1
]}

Robson, MD ^{[1
]}

Smith, SM ^{[1
]}

Johansen-Berg, H ^{[1
]}

机构：

[1] Univ Oxford, John Radcliffe Hosp, Oxford Ctr Funct Magnet Resonance Imaging Brain, Oxford OX3 9DU, England

来源：

NEUROIMAGE | 2006年 / 30卷 / 01期

基金：

英国医学研究理事会; 英国惠康基金; 英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1016/j.neuroimage.2005.09.036

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Functionally significant landmarks in the brain do not necessarily align with local sulcal and gyral architecture in a manner that is consistent across individuals. However, the functional specialisation underlying these landmarks is strongly constrained by the connectional architecture of the region. Here, we explore this relationship in the supplementary motor area (SMA) and pre-SMA in the medial frontal cortex of the human brain. Using diffusion tensor, conventional and functional MR imaging, we find that the location of the functional boundary between SMA and preSMA is more consistent with respect to specific features of the local white matter as it approaches neocortex than with respect to the local gyral and sulcal anatomy in the region. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：220 / 227

页数：8

共 27 条

[1]

ALEXANDER D, 1999, P 10 BRIT MACH VIS C

[2] Spatial transformations of diffusion tensor magnetic resonance images [J].