Protein/DNA/inorganic materials:: DNA binding to layered α-zirconium phosphate enhances bound protein structure and activity

被引：34

作者：

Bhambhani, A ^{[1
]}

Kumar, CV ^{[1
]}

机构：

[1] Univ Connecticut, Dept Chem, Storrs, CT 06269 USA

来源：

ADVANCED MATERIALS | 2006年 / 18卷 / 07期

关键词：

D O I：

10.1002/adma.200502230

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Successful intercalation of calf thymus DNA into the galleries of layered alpha zirconium phosphate (alpha-Zr(HPO4)(2) center dot H2O, alpha-ZrP) was facilitated by met-hemoglobin (Hb) and tetrabutylammonium (TBA) hydroxide. Intercalation of DNA, in turn, improved the properties of the co-intercalated protein. The protein structure, for example, was improved significantly and activities were enhanced by more than fivefold.

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页码：939 / +

页数：5

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