Analysis of pharmaceutical materials through the use of FT-Raman microprobe imaging

被引:2
作者
Rodriguez, C [1 ]
机构
[1] Nicolet Instrument Corp, Madison, WI 53711 USA
来源
BIOMEDICAL APPLICATIONS OF RAMAN SPECTROSCOPY, PROCEEDINGS OF | 1999年 / 3608卷
关键词
FT-Raman; imaging; pharmaceutical;
D O I
10.1117/12.345412
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The characterization of pharmaceutical solids has always been a concern for the pharmaceutical scientist, whether it be a formulator, analytical chemist or process chemist. Traditionally, characterization meant chemical purity, but today a more comprehensive characterization is crucial for a safe and consistent pharmaceutical product. Typically, FT-IR and FT-Raman are the vibrational techniques used to physically characterize solids. Recent advances in imaging technology have made FT-Raman microscopy another powerful tool for obtaining information of pharmaceutical products. This advance has made it possible to not only obtain chemical information, but gives the ability to spatially resolve the obtained information. Descriptions of various experimental procedures for analyzing formulated tablets as well as other materials of pharmaceutical interest using imaging techniques will be given.
引用
收藏
页码:37 / 43
页数:7
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