COMPUTER-ASSISTED INTRA-OPERATIVE MAGNETIC RESONANCE IMAGING MONITORING OF INTERSTITIAL LASER THERAPY IN THE BRAIN: A CASE REPORT

被引：19

作者：

Hata, Nobuhiko ^{[1
]}

Morrison, Paul R. ^{[1
]}

Kettenbach, Joachim ^{[1
]}

Black, Peter McL

Kikinis, Ron ^{[1
,2
]}

Jolesz, Ferenc A. ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Surg, Boston, MA 02115 USA

来源：

JOURNAL OF BIOMEDICAL OPTICS | 1998年 / 3卷 / 03期

基金：

日本学术振兴会;

关键词：

magnetic resonance imaging; interventional MRI; computer assisted surgery; CAS; surgery; minimally invasive surgery;

D O I：

10.1117/1.429857

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Hardware and software for a customized system to use magnetic resonance imaging (MRI) to noninvasively monitor laser-induced interstitial thermal therapy of brain tumors are reported. An open-configuration interventional MRI unit was used to guide optical fiber placement and monitor the deposition of laser energy into the targeted lesion. T1-weighted fast spin echo and gradient echo images were used to monitor the laser tissue interaction. The images were transferred from the MRI scanner to a customized research workstation and were processed intraoperatively. Newly developed software enabled rapid (27-221 ms) availability of calculated images. A case report is given showing images which reveal the laser-tissue interaction. The system design is feasible for on-line monitoring of interstitial laser therapy. (C) 1998 Society of Photo-Optical Instrumentation Engineers.

引用

页码：304 / 311

页数：8

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