Direct proline-catalyzed asymmetric α-aminoxylation of ketones

被引：259

作者：

Hayashi, Y ^{[1
]}

Yamaguchi, J ^{[1
]}

Sumiya, T ^{[1
]}

Shoji, M ^{[1
]}

机构：

[1] Sci Univ Tokyo, Fac Engn, Dept Ind Chem, Shinjuku Ku, Tokyo 1628601, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 09期

关键词：

asymmetric catalysis; ketones; oxidation; proline;

D O I：

10.1002/anie.200353085

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nitrosobenzene is the oxygen source in the direct catalytic enantioselective α-aminoxylation of ketones catalyzed by L-proline [Eq. (1)]. Versatile α-aminoxylated ketones are obtained in high yield and with excellent enantioselectivities.

引用

页码：1112 / 1115

页数：4

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