A systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data

被引：856

作者：

Klimisch, HJ

Andreae, M

Tillmann, U

机构：

[1] BASF Aktiengesellschaft

来源：

REGULATORY TOXICOLOGY AND PHARMACOLOGY | 1997年 / 25卷 / 01期

关键词：

D O I：

10.1006/rtph.1996.1076

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

The evaluation of the quality of data and their use in hazard and risk assessment as a systematic approach is described. Definitions are proposed for reliability, relevance, and adequancy of data. Reliability is differentiated into four categories. Criteria relating to international testing standards for categorizing reliability are developed. A systematic documentation of evaluating reliability especially for use in the IUCLID database is proposed. This approach is intended to harmonize data evaluation processes worldwide. It may help the expert in subsequent assessments and should increase the clarity of evaluation. (C) 1997 Academic Press.

引用

页码：1 / 5

页数：5